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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d0ce6584c1eea7c39a8ac6688bf3f7e313e9e9cc8eb8eebb7a2021f2b1a99b5' 
  AND token = 'oh2L2fsvNQS0P08dvc2nZbPtSXiXDa621nwJ6EjBc9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}