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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c48dbd6da163b4e84efc5e06d137d07009d2a8143705f3489616c72602c0463' 
  AND token = 'aHuNZ2doZT+JmoapqAco1S/QRurNayPanTm56K+UJv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}