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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da4d52c11e3192c768fbbcf86602a5d326af9d042be266668982fd5f21a0d497' 
  AND token = 'NHsXwAfulYJ99yCaEbQvkMJyw3XQcshF2NIBb2GdEMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}