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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2761907b77dc594666cdc560f1f8d7f34f4c95b2d05d6d9f85000b9b190e25f4' 
  AND token = 'PlvMhg2DYZjnvftLL1vO7XPnhsGWQYzodLRk1hQddl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}