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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df744a180799710ba6084f24e51001a12d1f6ea4d3814e1a30c0176052d7fdf0' 
  AND token = 'k3Fbb+1oeT3FO88Gwv+Ne4vExOHotAA1wYFJ5bEmbH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}