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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e41c8b6f55707fa99597b29917788408174fd3381d0a55db27485f93631e160' 
  AND token = 'yF1qA5LWeVxRqMyTuQxA1+GeoulXVFuVT/I9yWWfJO8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}