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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e5b162520e2e9ab7df70b9a9f452924c3d1c44a71343001e8905980e6979e9b' 
  AND token = 'rZYh/4Ug1OPCgZf589zRJRJhst/litbgrqivrhf2VHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}