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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1603e9435c0e151aa924a048e9de60d24bd428538622e6a22217e19e388c41a5' 
  AND token = '8J/JQFYf8MyNcptSuOsAbgkxb4QJCEDNqsryKUC2W0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}