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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e326d71051e7c11a567745099a90c796b386f7409cbd93a54a81e2d41f51698c' 
  AND token = '2HjksJ5+q8UmIeyg2AlaIzMWIR9xcyKb50VrYA8qj34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}