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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35fefae23337a288063fe0198ebc382c03d9d0c1ac370b5f451e70cffae8ff65' 
  AND token = 'kJQhP6lgU5zEcX3OuiHE2b0x+nCuENvH6qrQyjCa5xM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}