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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f7b8031706c975c23bc3103ddd56ff8ee062ca7d0cfe735ef2f93487880c278' 
  AND token = 'fmWZ+LAKX1tA+rQ1QKihnWDC508Atfu7pd2tuQOLWCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}