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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ce7057c2890d215cfda16a0d178f6a16c10e2cae0ffcaa6d0243a26ed34d1ac' 
  AND token = 'v5dWRzxAfUWt4F/N/iZp/8dklL6SDUh3AZJJAcqWx5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}