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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43b51c2eaf80be32d70c6650c197680801cd0cdb78cf53eb0450b8aa7a4b4ea3' 
  AND token = 'jzZuF52RBf5kgbni2AzNDLGmFwxTQNm/AHtmNZAOi5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}