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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c23bde043e798bd63d0304e5dd86c804d460240902e08bb2e1abc6feb09d39e' 
  AND token = 'xsUMkV0PRAheBjbkuBtC0fnBXHKDWDKgTnvmBV67dcs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}