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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd34412e864a2e3036e75dc101612c84c86b030c2c1547ad3c3f7c6135e9d3f3' 
  AND token = 'cIM7HNXVZLzEA2MWcR/kGvzbpqIQqwYAWSHMrAsG8ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}