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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b1e409eef41b01e0f3bdc6dd84d8db78374226461a3c3c2a1e7de86d401723f' 
  AND token = 'WsrSxSDIE16Jbs5cB6I5WZPPa2oRvDZCo+HA7oi+pqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}