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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b3de8a506e23f37e4302a727de6b3ec237f610551828e92be561575a3eaba06' 
  AND token = '7EBYoSTTmpm5ZwNvz7PoGVWcAG231Q9Cq1FJx3tYXx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}