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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72f2fac3faeb5660b7cf1018b0405da7432aca5b640d16560ecdb62237b49adb' 
  AND token = 'd5FF9Bssn/B4SQ+pMjZY2YTug1aE1Xj2t4itF94pf1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}