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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '266f220d1826d570e007be9714179d786959c4ef82577d4367b051a5e0eca03d' 
  AND token = 'Z6O7/ZN1H2qO02r4/dWia/znqMvfZHpPT73McBrIZBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}