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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db5df2b786dde77babbef9660cf862800a3e4abe6aa36dbcdae248c58bf627ca' 
  AND token = '5Nqax1m8hbzNGjc3ZkK3s2XMBRZ8VPYGCqC3yzZ+7Pc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}