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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ba2ba4487c85f4039305899f1d2b3d1224b1f104748b04a666026fa65e9aa730' 
  AND token = 'KfAGkP85DfJs1GRDE/WDS9o8nKHFELqQnKegh7nS3yg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}