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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b183002efa6ceb67d789fd7e10a24c88a7de0df56bf38eb2ba21f32a08889ef0' 
  AND token = 'mpWcfexn8rmn1sPF2ArfqUnzV1wygiAl1yfsA7VvOjA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}