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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '303f18741702d1352696fef88c65a35af4016ed9296599c53135b28a6c500851' 
  AND token = 'sSFgCGEZ/jA76y3JoxUBVf8j6idLeBFwpetcCQNDgYA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}