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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4379b91dd0b89e3a1c50cc8a075ffb4f9d67c85bf948ce22f369511f972e6991' 
  AND token = 'bVqDlodX1+yuxyGPRXR2APVE7WBod8zdymt852cQoR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}