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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77952f782f10ac17bb5c0385c8274f36637e8d4fab46554d6934e6069c140504' 
  AND token = 'QQZ77eE8cj+VLmr1uXSeYBdj45IhXJhaelU1lNlhJL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}