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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '814a1a75bc211d215d8515f64a8422e8a0060edfc04305bf3d7e6057922299ef' 
  AND token = 'zGYVVNIMH6Vk4Apb2fwzbOoSPltRiOb5rZflXqsOwpg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}