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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad918e91332e628036d73b077e1d75031b5915f22f162da0a8d35adbb965356c' 
  AND token = '+a7/G2LbKDu70EltVLest0pKOgF9vrGEZvCOMsgi3EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}