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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a99c4257c0a13da9152b0e1877274a0404966d7ddcf1c1981ca6a017947fde4' 
  AND token = 'LGW4jNZnRZmgKpGbZb+NEk+gbW+A7ogWq/7MSk3GkFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}