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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '277a8502c3ca91e9efe9a0c4f90ce83cde234488bf7090590b49b06899f95e73' 
  AND token = 'L3eND45R9WONZrrycEDuYqkrFTKhJrMBvT743g7r31Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}