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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b6a73eb64197d17e3b2fbd3c83577013c590a236cb328d6f036bc57252e1380' 
  AND token = 'lDgAltwfskOs/8EKEhtmOjjkKQEim1p5bfV/qSfUk/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}