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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fbc837a92334555e5a80604858372e5cc2e2f79c6bafcb5fc2052110514850a' 
  AND token = 'nx0GJ7RDz+Q3PmrHPjfv46cgQAviq4MlCbUtY69jqkY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}