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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '178b5b7088ec595237d9d8a3444cf11c72c4248dfaefb3203cc47492201fc86f' 
  AND token = 'QJUMcFmtZGMMEb4Z5u2PpgMiC3FzAMWTTLWMO7dj72s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}