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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05ed1c763146b781219464ef1cb7051fb5e9460f85f1bf1cfb3f83f3d5436f38' 
  AND token = 'E4oaTf6s6T0zv0wI/o3lzGff58QINd6WI1g4uim8Ca4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}