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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f27171930847d012f8696bd4fe9081bb13b4368cd4ffdb0fbb6504a0ea93839' 
  AND token = '6/NeMyoJK82Cxj30RSKLAaVVxQPfAzOeGdLdvUx99+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}