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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bbd9b319719e019117c0f0a64feda853f7e24a5a232ef40e1773f8e920fa294' 
  AND token = '62iuf/3UHdhB1A2J50KkR1kETxSXclUF5gAIGt5v4Oo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}