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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a011454f3ded569f9e3001c1dc33d17187f1dfc843e24c24e1ddc15677af3ce3' 
  AND token = 'B0djp6Y8s8QnjX9OJpuVuHT72LFled97YEy+UC00lwk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}