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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a576fea8d148ebb0a879383784a53e79c5cb3f619812f30206185c454ed98b4' 
  AND token = 'gdRbEIxU7AFRtnYiYBJax2hwRRrThfylXU9gEYT+z60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}