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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e370a6db2df4b60920bc8735bf162fb832c8a7fa7ca09cce6962361645dc9df' 
  AND token = '6EriYjAk5NL0SXL6CCZstTHAmJ6t9gp2UD/qTCF6tM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}