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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '398192b08088fb9705ae706674c858d4d7a75b90066b725fe6fcbaf9afe9248f' 
  AND token = '77LMo7L43YN090EGdvkPuFIbD6+VUqLUD1nzzye9OaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}