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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc5226a30a073ea370e1c32f3d6da3c156217a39791b31d5a3e8536d39d1c7df' 
  AND token = 'dVh9orueDod3/BVKQfnKiCrWp//euDJGXNHjuz+DVZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}