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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b836fa999820b56f913e5c5b69a79e75161081d55422ed21d5b0f024e5b4208f' 
  AND token = '1mwV3Qdj3iVJTIEaKBP5q2jeMvX3+Vn10By1fAoZaUI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}