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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65e62a0d0cccf3d4916deb25d3b9bc97e9b000f72fab7da5b1cbc3813db54cb5' 
  AND token = 'OUoXKErPGyc3UFklnUJwTfeXKqCvy5mPMN4Z0F+FJ/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}