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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27517631125f14503c1b3b179f39a42ee5390a1597518339b98583707b03a38c' 
  AND token = '7ZAMHhE9iOZZPA74Zf/z3YvXNXmOfdwTHOnM1D/+WZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}