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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a780825f0f11b215493dead8d0a80438d962d1f0ac0be6e5323050537ad43c6e' 
  AND token = '9pfTlgNGFwoklVXixGdXpCLPor5abhOnehpbqx8sg7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}