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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e2d48bbfc91438ffdab2fb4cd430eb3d2825c2e6f0bbd83511db503a58a65a5' 
  AND token = 'cQ4U8nq2PxNR+ygnq+3BvpCS3JmHu2vAUOP6Z4otD/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}