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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2092f16c0acc47fe4d3905d0ffc21af2aa5a72958526eb80d0bd410da5a1e8c4' 
  AND token = 'LcZO4dHteExmtzIN6jWCc9srxDZW7fYpncfUagzt5c8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}