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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '286be469d947f1edfe9d3a73002173f7e7fdcefdc65c1d986cb24057c40ba55a' 
  AND token = 'd76Ntcw45vGbSMBrz1MjmVnuVCw/WEjeRhA40oHBBMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}