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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eade58a0364024fe9f3e747e16be2785c5d7c364530c06a9413d473b4eed6d26' 
  AND token = '3Uk1RkF1+WKRKJurEiPyebBC2dTmvNBfHyXE39MsSXg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}