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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0be8806296e5f0fe4073440bc0e73c92f30ca9d1506db99997384d741adaa4bb' 
  AND token = 'VCRQSxzYtCp3hlAl3NMhpV4uxWArzbRlRFZ3tKf3uNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}