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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e65c5bdc0ad2e7acb6192050a3263c55970c1cb2726910e328db9f07567a17cf' 
  AND token = 'uvdxgK4HiAyc9Tw1zVLXqcpZ53Xis9aaiVC+JMLlxwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}